Resource Type

Journal Article 151

Conference Videos 14

Conference Topics 1

Year

2023 14

2022 13

2021 16

2020 14

2019 8

2018 5

2017 7

2016 3

2015 7

2014 6

2013 4

2012 5

2011 12

2010 2

2009 6

2008 5

2007 3

2006 6

2005 7

2003 1

open ︾

Keywords

response surface methodology 9

Response surface methodology 8

methodology 5

scientific and technological innovation 4

Wenchuan Earthquake 3

adsorption 3

China 2

Three Gorges Project 2

acupuncture 2

scientific 2

advanced energetic materials 1

energetic materials 1

energetic materials Chengdu 1

energetic materials frontier 1

energetic materials high-end forum 1

energetic materials high-end meeting 1

the 4th advanced energetic materials conference 1

20th century 1

N-methoxyl carbazole 1

open ︾

Search scope:

排序： Display mode:

Methodological challenges to human medical study

Yixin Zhong,Baoyan Liu,Hua Qu,Qi Xie

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 328-336 doi: 10.1007/s11684-014-0359-6

Abstract:

With the transformation of modern medicinal pattern, medical studies are confronted with methodological challenges. By analyzing two methodologies existing in the study of physical matter system and information system, the article points out that traditional Chinese medicine (TCM), especially the treatment based on syndrome differentiation, embodies information conception of methodological positions, while western medicine represents matter conception of methodological positions. It proposes a new way of thinking about combination of TCM and western medicine by combinating two kinds of methodological methods.

Keywords： medical paradigm     traditional Chinese medicine     western medicine     scientific view     scientific methodology    

HTML PDF Collect

Some Research Practice of Complex Engineering and Technology Problems and Considerations on the ScientificMethodology Concerned

Li Shihui

Strategic Study of CAE 2002, Volume 4, Issue 11,   Pages 71-81

Abstract: systems as their research objects, expounds the concept of TIM, and discusses some thinking about the scientificmethodology concerned.

Keywords： complex engineering and technology problem     practice     scientific methodology     combination of reductionism    

HTML PDF Collect

The Scientific Method and Introspection of PlagueHistory Research

Fu Youfeng

Strategic Study of CAE 2007, Volume 9, Issue 9,   Pages 19-29

Abstract: concerning the Chinese and English Encyclopedia,  the author gives out his own explanation of the scientific

Keywords： comparative medicine history     the plague history of Japan     beriberi     medical methodology     complexity    

HTML PDF Collect

Dynamic response surface methodology using Lasso regression for organic pharmaceutical synthesis

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 2,   Pages 221-236 doi: 10.1007/s11705-021-2061-y

Abstract: For utilizing such time-resolved data to model the dynamic behavior, dynamic response surface methodologyextents are modeled instead of the species concentrations, illustrates the versatility of the DRSM methodology

Keywords： data-driven modeling     pharmaceutical organic synthesis     Lasso regression     dynamic response surface methodology    

HTML PDF Collect

On Engineering Management Methodology

He Jishan,Xu Changshan,Wang Qinge,Guo Feng

Strategic Study of CAE 2014, Volume 16, Issue 10,   Pages 4-9

Abstract:

In this paper, the framework system of engineering management methodologyhas been constructed on the three levels: philosophical methodology, general methodology and specificmethodology.The main methods of philosophical methodology of engineering management include seeking truth from factsThe main methods of the specific methodology of engineering management are composed of case study and

Keywords： engineering     management methodology     philosophical     methodology     general     methodology     specific     methodology    

HTML PDF Collect

Search for a natural scientific measure of economy

John E COULTER

Frontiers of Environmental Science & Engineering 2011, Volume 5, Issue 1,   Pages 111-118 doi: 10.1007/s11783-011-0285-7

Abstract: Through human history, wealth has been measured in grain, gold, and, now, dollars. Though counterfeiting of coins and notes goes back a long way, it is only with electronic financial accounting in a global economy tainted by toxic loans and imaginary funds that there is an urgency to search for a realistic objective way to monitor and regulate what we are doing to our Earth and ourselves. Various schemes using analysis of utility functions, oil equivalents, entropy, energy, and other units have been tried and, while helping to understand some basic processes and flows, have always been swamped by the machinations of financiers and the attention big sums of money attract. Now, the concept of exergy, pioneered in Eastern Europe in the 1950s, is being researched, developed, and applied, especially in China, driven by the desperation to measure the reality beyond the twin specters of global financial and environmental crises. A rough inventory of the matter in the biosphere at the coordinate details of an angstrom and an appreciation of how humans harness and manipulate electromagnetic forces can be enlightening as to what is and is not sustainable. Without that understanding, any financial estimate and proposed stimulus packages or IMF reform will be wildly wrong and may even be headed in the wrong direction.

Keywords： climate change     financial crisis     energy     exergy     environment    

HTML PDF Collect

of a combined approach for improvement and optimization of karanja biodiesel using response surface methodology

Sunil DHINGRA, Gian BHUSHAN, Kashyap Kumar DUBEY

Frontiers in Energy 2013, Volume 7, Issue 4,   Pages 495-505 doi: 10.1007/s11708-013-0267-5

Abstract: This paper described the production of karanja biodiesel using response surface methodology (RSM) and

Keywords： optimization of karanja biodiesel     genetic algorithm (GA)     response surface methodology (RSM)     percentage    

HTML PDF Collect

Rethinking the tendering frameworks of construction contractors in the context of a soft systems methodology

Stephen URQUHART, Andrew WHYTE

Frontiers of Engineering Management 2018, Volume 5, Issue 3,   Pages 369-380 doi: 10.15302/J-FEM-2018019

Abstract: A new way of presenting the ITP of contractors is assessed using a soft systems methodology (SSM) approach

Keywords： contractor     corporate governance     humanistic     risk     soft systems methodology     tendering procedures    

HTML PDF Collect

Exploring the methodology and application of clinical pathway in evidence-based Chinese medicine

Sicheng Wang, He Yu, Jianping Liu, Baoyan Liu

Frontiers of Medicine 2011, Volume 5, Issue 2,   Pages 157-162 doi: 10.1007/s11684-011-0128-8

Abstract: explored the application of the clinical pathway of evidence-based Chinese medicine incorporated with the methodology

Keywords： evidence-based medicine     clinical pathway     methodology     concept     technical difficulty    

HTML PDF Collect

Optimization of the O/HO process with response surface methodology for pretreatment of mother liquor

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 4, doi: 10.1007/s11783-020-1371-5

Abstract:

• Real ML-GFW with high salinity and high organics was degraded by O3/H2O2 process.

Keywords： High organic matters     Gas field wastewater     O3/H2O2     Response surface methodology    

HTML PDF Collect

A conceptual methodology for simultaneous optimization of water and heat with non-isothermal mixing

Yanlong Hou, Wanni Xie, Zhenya Duan, Jingtao Wang

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 2,   Pages 154-165 doi: 10.1007/s11705-016-1593-z

Abstract: A new conceptual methodology is proposed to simultaneously integrate water allocation and energy networks

Keywords： simultaneous integration     non-isothermal mixing     multi-target optimization     water and energy networks    

HTML PDF Collect

A highly efficient methodology for the preparation of

Yongxin Zhang, Shucheng Wang, Yaodong Huang

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 3,   Pages 679-686 doi: 10.1007/s11705-020-1979-9

Abstract: Based on this methodology, the first total synthesis of 3,3′-[oxybis(methylene)]bis(9-methoxy-9 -carbazole

Keywords： N-methoxyl carbazole     dimeric N-methoxyl carbazole     alkaloid     total synthesis     double N-arylation of methoxyamine    

HTML PDF Collect

Complex Financial Information System Engineering Management from the Perspective of Meta-synthesis Methodology—with

Hong-feng Chai,Quan Sun

Frontiers of Engineering Management 2016, Volume 3, Issue 4,   Pages 404-413 doi: 10.15302/J-FEM-2016037

Abstract: By integrating the meta-synthesis methodology and the financial information system engineering, the paper

Keywords： financial information system     meta-synthesis methodology     bank card     information exchange    

HTML PDF Collect

Innovating engineering technology supporting scientific development

Du Xiangwan

Strategic Study of CAE 2009, Volume 11, Issue 4,   Pages 4-8

Abstract:

This paper reviewed the important scientific progress and engineering

Keywords： technology     engineering     innovation     scientific development    

HTML PDF Collect

Machine learning-based solubility prediction and methodology evaluation of active pharmaceutical ingredients

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 4,   Pages 523-535 doi: 10.1007/s11705-021-2083-5

Abstract: Solubility has been widely regarded as a fundamental property of small molecule drugs and drug candidates, as it has a profound impact on the crystallization process. Solubility prediction, as an alternative to experiments which can reduce waste and improve crystallization process efficiency, has attracted increasing attention. However, there are still many urgent challenges thus far. Herein we used seven descriptors based on understanding dissolution behavior to establish two solubility prediction models by machine learning algorithms. The solubility data of 120 active pharmaceutical ingredients (APIs) in ethanol were considered in the prediction models, which were constructed by random decision forests and artificial neural network with optimized data structure and model accuracy. Furthermore, a comparison with traditional prediction methods including the modified solubility equation and the quantitative structure-property relationships model was carried out. The highest accuracy shown by the testing set proves that the ML models have the best solubility prediction ability. Multiple linear regression and stepwise regression were used to further investigate the critical factor in determining solubility value. The results revealed that the API properties and the solute-solvent interaction both provide a nonnegligible contribution to the solubility value.

Keywords： solubility prediction     machine learning     artificial neural network     random decision forests    

HTML PDF Collect

Title Author Date Type Operation

Methodological challenges to human medical study

Yixin Zhong,Baoyan Liu,Hua Qu,Qi Xie

Journal Article

Some Research Practice of Complex Engineering and Technology Problems and Considerations on the ScientificMethodology Concerned

Li Shihui

Journal Article

The Scientific Method and Introspection of PlagueHistory Research

Fu Youfeng

Journal Article

Dynamic response surface methodology using Lasso regression for organic pharmaceutical synthesis

Journal Article

On Engineering Management Methodology

He Jishan,Xu Changshan,Wang Qinge,Guo Feng

Journal Article

Search for a natural scientific measure of economy

John E COULTER

Journal Article

of a combined approach for improvement and optimization of karanja biodiesel using response surface methodology

Sunil DHINGRA, Gian BHUSHAN, Kashyap Kumar DUBEY

Journal Article

Rethinking the tendering frameworks of construction contractors in the context of a soft systems methodology

Stephen URQUHART, Andrew WHYTE

Journal Article

Exploring the methodology and application of clinical pathway in evidence-based Chinese medicine

Sicheng Wang, He Yu, Jianping Liu, Baoyan Liu

Journal Article

Optimization of the O/HO process with response surface methodology for pretreatment of mother liquor

Journal Article

A conceptual methodology for simultaneous optimization of water and heat with non-isothermal mixing

Yanlong Hou, Wanni Xie, Zhenya Duan, Jingtao Wang

Journal Article

A highly efficient methodology for the preparation of

Yongxin Zhang, Shucheng Wang, Yaodong Huang

Journal Article

Complex Financial Information System Engineering Management from the Perspective of Meta-synthesis Methodology—with

Hong-feng Chai,Quan Sun

Journal Article

Innovating engineering technology supporting scientific development

Du Xiangwan

Journal Article

Machine learning-based solubility prediction and methodology evaluation of active pharmaceutical ingredients

Journal Article